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Besides ATF4, another transcription factor that regulates xCT expression is the nuclear factor erythroid 2-related factor 2 (NRF2) via the antioxidant response element (ARE) present in the promoter region of xCT gene (40, 41)

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doi: 10.1136/annrheumdis-2021-220920 124 PeruginoCAWallaceZSZackDJQuinnSMPomaAFernandesADet al

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[Google Scholar] 36.Labarrere CA, Kassab GS

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